BDBM50228247 CHEMBL38017::LY-197055

SMILES CC1CC(=O)NN=C1c1ccc2NC(=O)C(C)(C)c2c1

InChI Key InChIKey=POOZXNMBPQYVQV-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50228247   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL

LigandBDBM50228247(LY-197055 | CHEMBL38017)Copy SMILESCopy InChI

Affinity DataIC50: 13nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/22/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Eli Lilly

Curated by ChEMBL

LigandBDBM50228247(LY-197055 | CHEMBL38017)Copy SMILESCopy InChI

Affinity DataKi:  0.540nMAssay Description:Displacement [3H]LY-186,126 from phosphodiesterase 4 of myocardial vesiclesMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
1/8/2019
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL