BDBM50212626 LY-255283

SMILES CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1

InChI Key InChIKey=WCGXJPFHTHQNJL-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50212626   

LigandChemical structure of BindingDB Monomer ID 50212626BDBM50212626(LY-255283)
Affinity DataKi:  77nMAssay Description:Inhibition of specific binding of [3H]-LTB4 to LTB4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50212626BDBM50212626(LY-255283)
Affinity DataIC50: 85nMAssay Description:Inhibition of specific binding of [3H]LTB4 to LTB4 receptor in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

TargetLeukotriene B4 receptor 2(Human)
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212626BDBM50212626(LY-255283)
Affinity DataIC50: 144nMAssay Description:Displacement of FITC-labeled tracer from Lumi4 Tb-labeled BLT2 (unknown origin) expressed in CHO-K1 cells incubated for 1 hrs by Tag-lite displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetLeukotriene B4 receptor 2(Human)
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212626BDBM50212626(LY-255283)
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]LTB4 from HA-epitope tagged human BLT2 expressed in CHOK1 cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed