BDBM50084140 4-((S)-Amino-carboxy-methyl)-3-methyl-benzoic acid::CHEMBL94631::LY-367385

SMILES Cc1cc(ccc1[C@H](N)C(O)=O)C(O)=O

InChI Key InChIKey=SGIKDIUCJAUSRD-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50084140   

TargetMetabotropic glutamate receptor 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50084140(LY-367385 | 4-((S)-Amino-carboxy-methyl)-3-methyl-...)
Affinity DataIC50: 8.00E+3nMAssay Description:Negative allosteric modulation of human mGluR1alpha expressed in syrian hamster AV-12 cells assessed as inhibition of quisqualate-induced phosphoinos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50084140(LY-367385 | 4-((S)-Amino-carboxy-methyl)-3-methyl-...)
Affinity DataIC50: 8.80E+3nMAssay Description:Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50084140(LY-367385 | 4-((S)-Amino-carboxy-methyl)-3-methyl-...)
Affinity DataIC50: 1.90E+4nMAssay Description:Compound was tested for functional response of human metabotropic glutamate receptor mGluR1-alpha expressed in AV-12 cells by measuring inhibitory co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMetabotropic glutamate receptor 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50084140(LY-367385 | 4-((S)-Amino-carboxy-methyl)-3-methyl-...)
Affinity DataIC50: 1.90E+4nMAssay Description:Compound was tested for functional response of human metabotropic glutamate receptor mGluR1-alpha expressed in AV-12 cells by measuring inhibitory co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMetabotropic glutamate receptor 5(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM50084140(LY-367385 | 4-((S)-Amino-carboxy-methyl)-3-methyl-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM50084140(LY-367385 | 4-((S)-Amino-carboxy-methyl)-3-methyl-...)
Affinity DataIC50: 3.00E+5nMAssay Description:Compound was tested for functional response of human metabotropic glutamate receptor mGluR5a expressed in AV-12 cells by measuring inhibitory concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMetabotropic glutamate receptor 5(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM50084140(LY-367385 | 4-((S)-Amino-carboxy-methyl)-3-methyl-...)
Affinity DataIC50: 3.00E+5nMAssay Description:Compound was tested for functional response of human metabotropic glutamate receptor mGluR5a expressed in AV-12 cells by measuring inhibitory concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMetabotropic glutamate receptor 5(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM50084140(LY-367385 | 4-((S)-Amino-carboxy-methyl)-3-methyl-...)
Affinity DataIC50: 3.00E+5nMAssay Description:Compound was tested for functional response of human metabotropic glutamate receptor mGluR5a expressed in AV-12 cells by measuring inhibitory concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMetabotropic glutamate receptor 1(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50084140(LY-367385 | 4-((S)-Amino-carboxy-methyl)-3-methyl-...)
Affinity DataIC50: 3.00E+5nMAssay Description:Compound was tested for functional response of human metabotropic glutamate receptor mGluR1-alpha expressed in AV-12 cells by measuring inhibitory co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article