BDBM50458119 Leusa

SMILES CC(C)C[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key InChIKey=XFEDFDTWJLGMBO-LEJQEAHTSA-N

Data  1 KI  1 IC50

PDB links: 11 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50458119   

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50458119(Leusa)
Affinity DataKi:  0.139nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Leucyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherichi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetLeucine--tRNA ligase, cytoplasmic(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50458119(Leusa)
Affinity DataIC50:  22nMAssay Description:Inhibition of catalytic activity of LRS (unknown origin) by aminoleucylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)