BDBM50311438 CHEMBL4169942

SMILES CC(=O)n1cc(C(=O)Nc2cc(COC3CCCCO3)cc(c2)C(O)=O)c2ccccc12

InChI Key InChIKey=MBYTWRXIPXJQJP-UHFFFAOYSA-N

Data  8 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50311438   

TargetHistone acetyltransferase p300(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50311438(CHEMBL4169942)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of biotinylated-H4KAc4 binding to human His6-tagged EP300 (A1040 to G1161 residues) expressed in Escherichia coli BL21(DE3) after 2.5 hrs ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetBromodomain-containing protein 4(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50311438(CHEMBL4169942)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of biotinylated-H4KAc4 binding to human His6-tagged BRD4 bromodomain-1 (N44 to E168 residues) expressed in Escherichia coli BL21(DE3) afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTranscription initiation factor TFIID subunit 1(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50311438(CHEMBL4169942)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of biotinylated-H4KAc4 binding to human His6-tagged TAF-1 (R1377 to D1503 residues) expressed in Escherichia coli BL21(DE3) after 2.5 hrs ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCREB-binding protein(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50311438(CHEMBL4169942)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of biotinylated-H4KAc4 binding to human His6-tagged CBP (R1081 to G1197 residues) expressed in Escherichia coli BL21(DE3) after 2.5 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetBromodomain-containing protein 9(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50311438(CHEMBL4169942)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of biotinylated-H4KAc4 binding to human His6-tagged BRD9 (L14 to Q134 residues) expressed in Escherichia coli BL21(DE3) after 2.5 hrs by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTranscription intermediary factor 1-alpha(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50311438(CHEMBL4169942)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of biotinylated-H4KAc4 binding to human His6-tagged TIF-1 (G896 to E1014 residues) expressed in Escherichia coli BL21(DE3) after 2.5 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone acetyltransferase KAT2B(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50311438(CHEMBL4169942)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of biotinylated-H4KAc4 binding to human His6-tagged PCAF (G715 to D831 residues) expressed in Escherichia coli BL21(DE3) after 2.5 hrs by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50311438(CHEMBL4169942)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of biotinylated-H4KAc4 binding to human His6-tagged BAZ2B (S1858 to S1972 residues) expressed in Escherichia coli BL21(DE3) after 2.5 hrs ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed