BDBM50371402 MERIOLIN 3
SMILES COc1ccnc2[nH]cc(-c3ccnc(N)n3)c12
InChI Key InChIKey=GGEWEQJWGGJUHO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50371402
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of rat recombinant GST-DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in insect cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in insect cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant CDK2/cyclin A after 30 mins by [gamma-33P]ATP based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in baculovirus infected Sf9 insect cells using pRB (773 to 928 residues) as substrate after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant GST-CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in baculovirus infected Sf9 insect cells after 30 mins by [gamma-33P]ATP based scintillation count...More data for this Ligand-Target Pair