BDBM60419 BDBM50295658::NAM

SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCCN1C(=O)C=CC1=O

InChI Key InChIKey=GZNZRHSGGQUYAP-DOFZRALJSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 60419   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM60419(BDBM50295658 | NAM)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of Wistar rat brain FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM60419(BDBM50295658 | NAM)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant MGL by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM60419(BDBM50295658 | NAM)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of human MGLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM60419(BDBM50295658 | NAM)
Affinity DataIC50:  2.18E+3nMAssay Description:Inhibition of human FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM60419(BDBM50295658 | NAM)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of human cerebellar membranes MAGL-like activity preincubated for 30 mins followed by 2-AG substrate addition after 90 mins by HPLC analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM60419(BDBM50295658 | NAM)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human MAGL expressed in Escherichia coli using 6-methoxy-4-methylcoumarin ester as substrate after 3 hrs by mass spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM60419(BDBM50295658 | NAM)
Affinity DataIC50:  140nMAssay Description:Inhibition of MAGL in rat cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM60419(BDBM50295658 | NAM)
Affinity DataIC50:  140nMAssay Description:Inhibition of MAGL from Wistar rat brain membranes using 2-AG as substrate after 90 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM60419(BDBM50295658 | NAM)
Affinity DataIC50:  140nMAssay Description:Inhibition of rat cerebellar membranes MAGL-like activity preincubated for 30 mins followed by 2-AG substrate addition after 90 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM60419(BDBM50295658 | NAM)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAAH in Sprague-Dawley rat brain microsomes assessed as N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide conversion to 4-pyren-1-ylbutanoic ac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed