BDBM50414948 CHEMBL121516::NSC-527035

SMILES S=C(SSC(=S)N1CCCCC1)N1CCCCC1

InChI Key InChIKey=KNBRWWCHBRQLNY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50414948   

TargetAldehyde dehydrogenase 1A1(Human)
Umm Al-Qura University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414948BDBM50414948(NSC-527035 | CHEMBL121516)
Affinity DataIC50: 50nMAssay Description:Inhibition of ALDH1A1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Taiyuan University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414948BDBM50414948(NSC-527035 | CHEMBL121516)
Affinity DataIC50: 70nMAssay Description:Inhibition of HSP90 (unknown origin) assessed as HER2 degradation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMonoglyceride lipase(Human)
Universite Catholique De Louvain

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414948BDBM50414948(NSC-527035 | CHEMBL121516)
Affinity DataIC50: 316nMAssay Description:Inhibition of human MGL activity using [3H]2-oleoylglycerol substrate by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414948BDBM50414948(NSC-527035 | CHEMBL121516)
Affinity DataIC50: 510nMAssay Description:Inhibition of human PHGDH by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Taiyuan University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414948BDBM50414948(NSC-527035 | CHEMBL121516)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as reduction in Abeta42 level by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetAldehyde dehydrogenase, mitochondrial(Human)
Umm Al-Qura University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414948BDBM50414948(NSC-527035 | CHEMBL121516)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of ALDH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414948BDBM50414948(NSC-527035 | CHEMBL121516)
Affinity DataIC50: 8.78E+3nMAssay Description:Inhibition of wild-type full-length human liver FBPase expressed in Escherichia coli BL21 (DE3) using FBP as substrate by malachite green dye based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Taiyuan University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414948BDBM50414948(NSC-527035 | CHEMBL121516)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of hPD-1/hPD-L1 immune checkpoint using PD-L1 expressing human aAPCs and PD-1 expressing human Jurkat cells assessed as activation of effe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetFatty-acid amide hydrolase 1(Human)
Universite Catholique De Louvain

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414948BDBM50414948(NSC-527035 | CHEMBL121516)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant FAAH-maltose binding proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed