BDBM318447 NSC332396::US9624235, Compound 5

SMILES Cc1[nH]n(-c2ccccc2)c(=O)c1\C=N\Nc1cc(C)nc2cc3OCOc3cc12

InChI Key InChIKey=NVUNMXBZMBSWRJ-FOKLQQMPSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 318447   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM318447(NSC332396 | US9624235, Compound 5)
Affinity DataKi:  680nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM318447(NSC332396 | US9624235, Compound 5)
Affinity DataIC50:  3.44E+4nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent