BDBM50647948 Trichlormethiazide::Triclormetiazida::Trichloromethiazide::NSC-61560::Metahydrin::Naqua::Trichlorex::Trichlormas::Trichlormethiazide component of metatensin::Trichlormethiazide component of naquival

SMILES NS(=O)(=O)c1cc2c(cc1Cl)NC(C(Cl)Cl)NS2(=O)=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50647948   

TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50647948(Trichlormethiazide | Triclormetiazida | Trichlorom...)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to human recombinant CA II assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50647948(Trichlormethiazide | Triclormetiazida | Trichlorom...)
Affinity DataKd:  2.60E+3nMAssay Description:Displacement of dansylamide from human recombinant CA II expressed in Escherichia coli BL21 DE3 assessed as dissociation constant by fluorescence mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 3(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50647948(Trichlormethiazide | Triclormetiazida | Trichlorom...)
Affinity DataKd: >2.00E+5nMAssay Description:Binding affinity to human recombinant CA III assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed