BDBM50622714 BOCODEPSIN BESYLATE::Bocodepsin besylate::OKI-179::OKI179::Oki-179

SMILES CC(C)[C@H](N)C(=O)SCCC1=C[C@@H]3CC(=O)N1Cc2nc(cs2)C(=O)NC(C)(C)C(=O)N[C@@H](C(C)C)C(=O)O3

InChI Key InChIKey=RMUQRXWMIDWKAH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50622714   

TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50622714(OKI179 | Bocodepsin besylate | BOCODEPSIN BESYLATE)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant HDAC1 using ZMAL (Z-(Ac)Lys-AMC) as fluorogenic substrate preincubated for 5 mins followed by substrate addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50622714(OKI179 | Bocodepsin besylate | BOCODEPSIN BESYLATE)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant full length human HDAC3 expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50622714(OKI179 | Bocodepsin besylate | BOCODEPSIN BESYLATE)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human full length recombinant HDAC2 expressed in baculovirus infected Sf9 cells using RHKKAc as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed