BDBM23316 7-phenyl-1-{pyrido[2,3-d][1,3]oxazol-2-yl}heptan-1-one::CHEMBL367966::OL-92
SMILES O=C(CCCCCCc1ccccc1)c1nc2ncccc2o1
InChI Key InChIKey=OVFUWDCWLWBDJD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 23316
Affinity DataKi: 0.280nMAssay Description:Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Inhibitor affinity of the compound towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or ...More data for this Ligand-Target Pair
Affinity DataIC50: 525nMAssay Description:Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assayMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration against Fatty-acid amide hydrolaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against Triacylglycerol hydrolaseMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration of fatty acid amide hydrolase using FP-Rh radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration of triacylgylcerol hydrolase using FP-Rh radioligandMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibitory concentration against fatty acid amide hydrolaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.316nMpH: 9.0 T: 37°CAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [3H]anandamide was evaluated by using rat brain homogenate preparations. [3H]Ethanola...More data for this Ligand-Target Pair