BDBM50119817 2-Methyl-N-[4-(2,3,4,5-tetrahydro-benzo[b][1,4]diazepine-1-carbonyl)-phenyl]-benzamide::CHEMBL106229::OPC-31260

SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCNc2ccccc12

InChI Key InChIKey=HZOABPDJUQEYFK-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50119817   

TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50119817(OPC-31260 | 2-Methyl-N-[4-(2,3,4,5-tetrahydro-benz...)
Affinity DataIC50: 28nMAssay Description:Inhibition of [3H]Arg-vasopressin binding to recombinant human vasopressin V2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50119817(OPC-31260 | 2-Methyl-N-[4-(2,3,4,5-tetrahydro-benz...)
Affinity DataKi:  160nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50119817(OPC-31260 | 2-Methyl-N-[4-(2,3,4,5-tetrahydro-benz...)
Affinity DataIC50: 250nMAssay Description:Inhibition of [3H]Arg-vasopressin binding to recombinant human vasopressin V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50119817(OPC-31260 | 2-Methyl-N-[4-(2,3,4,5-tetrahydro-benz...)
Affinity DataKi:  890nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V1a receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed