BDBM50635225 Tamnorzatinib::Ono 7475::Ono-7475::ONO-7475

SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4cc5c(n(-c6ccccc6)c4=O)CCCC5=O)nc3)c2cc1OC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50635225   

TargetTyrosine-protein kinase receptor UFO(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50635225(Tamnorzatinib | Ono 7475 | Ono-7475 | ONO-7475)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of AXL (unknown origin) by HTRF kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50635225(Tamnorzatinib | Ono 7475 | Ono-7475 | ONO-7475)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of AXL (unknown origin) preincubated for 15 mins followed by substrate and ATP addition and measured after 3 hrs by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50635225(Tamnorzatinib | Ono 7475 | Ono-7475 | ONO-7475)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of MER (unknown origin) preincubated for 15 mins followed by substrate and ATP addition and measured after 3 hrs by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed