BDBM82013 8-(2-Amino-4-chloro-phenyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione(PACPX)::8-(2-Amino-4-chlorophenyl)-1,3-dipropylxanthine::CAS_92411::CHEMBL273671::NSC_92411::PACPX

SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccc(Cl)cc1N

InChI Key InChIKey=SENJBFBVCXOUFE-UHFFFAOYSA-N

Data  12 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 82013   

TargetAdenosine receptor A1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM82013(8-(2-Amino-4-chloro-phenyl)-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  0.0220nMAssay Description:Inhibitory activity against adenosine A1 receptor in bovine brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM82013(8-(2-Amino-4-chloro-phenyl)-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM82013(8-(2-Amino-4-chloro-phenyl)-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity of the compound against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM82013(8-(2-Amino-4-chloro-phenyl)-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity against adenosine A1 receptor using [3H]-CHA or [3H]PIA as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM82013(8-(2-Amino-4-chloro-phenyl)-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  2.5nMAssay Description:Antagonism of binding of 1 nM [3H]cyclohexyladenosine to adenosine A1 receptors on rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM82013(8-(2-Amino-4-chloro-phenyl)-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  2.51nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM82013(8-(2-Amino-4-chloro-phenyl)-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  4.80nMAssay Description:Inhibition of [3H]-CHA binding to Adenosine A1 receptor in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM82013(8-(2-Amino-4-chloro-phenyl)-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  6.80nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Warner-Lambert/Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM82013(8-(2-Amino-4-chloro-phenyl)-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  91.9nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetAdenosine receptor A2a/A2b(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM82013(8-(2-Amino-4-chloro-phenyl)-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity against A2 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM82013(8-(2-Amino-4-chloro-phenyl)-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  1.00E+3nMAssay Description:Antagonism of cyclic [3H]AMP accumulation in guinea pig cerebral cortical slices (elicited by 15 uM 2-chloroadenosine at adenosine A2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Warner-Lambert/Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM82013(8-(2-Amino-4-chloro-phenyl)-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM82013(8-(2-Amino-4-chloro-phenyl)-1,3-dipropyl-3,7-dihyd...)
Affinity DataIC50:  0.0500nMAssay Description:Binding affinity against bovine brain adenosine A1 receptor by using N6-[3H]- cyclohexyladenosineChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed