BDBM50038526 1-(2,6-Diisopropyl-phenyl)-3-(1-phenyl-cyclopentylmethyl)-urea::CHEMBL296055::PD-129337

SMILES CC(C)c1cccc(C(C)C)c1NC(=O)NCC1(CCCC1)c1ccccc1

InChI Key InChIKey=YDMKLNVDRGIRBS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50038526   

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50038526(1-(2,6-Diisopropyl-phenyl)-3-(1-phenyl-cyclopentyl...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibitory activity against ACAT was determined in rabbit intestinal microsome from cholesterol-fed animalsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSterol O-acyltransferase 1(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50038526(1-(2,6-Diisopropyl-phenyl)-3-(1-phenyl-cyclopentyl...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibition of rat intestinal acyl coenzyme A:cholesterol acyltransferase using [1-14C]oleolyl-CoAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50038526(1-(2,6-Diisopropyl-phenyl)-3-(1-phenyl-cyclopentyl...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50038526(1-(2,6-Diisopropyl-phenyl)-3-(1-phenyl-cyclopentyl...)
Affinity DataIC50:  17nMAssay Description:Tested for in vitro inhibition against Acyl coenzyme A:cholesterol acyltransferase of intestinal microsomes in cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed