BDBM50450813 Atripla::CHEBI:63625::GS-1275::PMP-A::Tenofovir::Truvada
SMILES C[C@H](Cn1cnc2c(N)ncnc12)OCP(O)(O)=O
InChI Key InChIKey=SGOIRFVFHAKUTI-ZCFIWIBFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50450813
Affinity DataEC50: 242nMAssay Description:Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataKd: 3.20E+3nMAssay Description:Binding affinity to ternary complex of HIV1 reverse transcriptase with primer/template in presence of dCTP substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of wild type HIV 3B reverse transcriptase in MT2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.58E+4nMAssay Description:Inhibition of human recombinant CYP3A4 expressed in insect microsome using 7-benzyloxy-4-trifluoromethylcoumarin as a substrate incubated for 30 mins...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Michigan State University
Michigan State University
Affinity DataIC50: 1.42E+4nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
Affinity DataIC50: 1.18E+4nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6 expressed in insect microsome using (3-[2-(N,N-dimethyl-N-methylammonium)-ethyl]-7-methoxy-4-methylcoumarin io...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition on HIV1 reverse transcriptase p66/p51More data for this Ligand-Target Pair