BDBM50019443 1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol::1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol((-)-Pindolol)::1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol(pindolol)::1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol::LB-46::PINDOLOL::PINDOLOL,(-)::PRINODOLOL::VISKAZIDE::VISKEN

SMILES CC(C)NCC(O)COc1cccc2[nH]ccc12

InChI Key InChIKey=JZQKKSLKJUAGIC-UHFFFAOYSA-N

Data  72 KI  5 IC50  7 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 85 hits for monomerid = 50019443   

TargetBeta-2 adrenergic receptor(Rat)
Niigata College of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  0.320nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-2 adrenergic receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity at human adrenergic beta2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetBeta-1 adrenergic receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  0.520nMAssay Description:Binding affinity at human adrenergic beta1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetBeta-1 adrenergic receptor(Rat)
Niigata College of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  0.660nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-2 adrenergic receptor(Guinea pig)
Ohio State University

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  1.14nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetBeta-1 adrenergic receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  1.94nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank


TargetBeta-1 adrenergic receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  2.60nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetBeta-2 adrenergic receptor(Guinea pig)
Ohio State University

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  2.63nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetBeta-2 adrenergic receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  4.80nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetBeta-1 adrenergic receptor(Guinea pig)
Ohio State University

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  7.24nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

Target5-hydroxytryptamine receptor 1A(Human)
Sorbonne University

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  15nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

Target5-hydroxytryptamine receptor 1A(Human)
Sorbonne University

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  17.8nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  20nMAssay Description:Evaluated for the binding affinity to hippocampus striatal membranes at 5-hydroxytryptamine 1A receptor binding site by using [3H]-8-OH- DPAT as a ra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Sorbonne University

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]DPAT from human 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  22nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1B(Rat)
University of Texas

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  24nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

Target5-hydroxytryptamine receptor 1A(Human)
Sorbonne University

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  24nMAssay Description:Displacement of specific [3H]- 5-HT binding to cloned human 5-hydroxytryptamine 1A receptor stably expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Sorbonne University

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  28nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Sorbonne University

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  28.2nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  31nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Sorbonne University

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  33.1nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Sorbonne University

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  33.3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Sorbonne University

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  37.1nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-3 adrenergic receptor(Human)
UniversitÄT WÜRzburg

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  44.1nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  47nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1B(Rat)
University of Texas

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  58.9nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Sorbonne University

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  61.1nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Sorbonne University

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  61.6nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1B(Rat)
University of Texas

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  61.6nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1B(Mouse)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  63.1nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1B(Rat)
University of Texas

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  80nMAssay Description:Binding affinity (Ki) to rat cortical membranes at 5-HT1B binding site by using [125 I] ICYP as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Sorbonne University

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  81nMAssay Description:Antagonist activity at human 5HT1A expressed in mouse LM(tK-) cells assessed as inhibition of 5HT-stimulated [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  100nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Sorbonne University

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  110nMAssay Description:Inhibition constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1B(Rat)
University of Texas

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  151nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Guinea pig)
Monash University

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  501nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Rat)
The Scripps Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  545nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Rat)
The Scripps Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

Target5-hydroxytryptamine receptor 5B(Rat)
University of Heidelberg Zmbh

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Rat)
The Scripps Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

Target5-hydroxytryptamine receptor 1B(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  1.20E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2B(Human)
Vernalis Research

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  2.19E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Rat)
The Scripps Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  2.50E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1B(Human)
Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  2.60E+3nMAssay Description:Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


Target5-hydroxytryptamine receptor 1B(Human)
Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  2.60E+3nMAssay Description:Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


Target5-hydroxytryptamine receptor 1B(Human)
Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  4.10E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


Target5-hydroxytryptamine receptor 1D(Human)
Synaptic Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  4.90E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1B(Rat)
University of Texas

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  5.80E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

Target5-hydroxytryptamine 1D receptor(Bovine)
Synaptic Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  6.30E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 3A(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  6.61E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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