BDBM50130230 CHEMBL78862::N-(6-Chloro-9H-beta-carbolin-8-yl)-benzamide::N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)benzamide::PS-1145

SMILES Clc1cc(NC(=O)c2ccccc2)c2[nH]c3cnccc3c2c1

InChI Key InChIKey=HSOCWLKMVJTAGZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50130230   

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50130230(CHEMBL78862 | N-(6-Chloro-9H-beta-carbolin-8-yl)-b...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against IkappaB kinase(IKK) isolated from HeLa cells activated with recombinant MEEK1 in an ELISA phosphorylaton assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50130230(CHEMBL78862 | N-(6-Chloro-9H-beta-carbolin-8-yl)-b...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity against protein kinase A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50130230(CHEMBL78862 | N-(6-Chloro-9H-beta-carbolin-8-yl)-b...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity against protein kinase C.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed