BDBM50582214 ATALUREN::Ataluren::PTC-124::PTC124::Translarna::US11744839, Compound of formula 4
SMILES OC(=O)c1cccc(c1)-c1noc(n1)-c1ccccc1F
InChI Key InChIKey=OOUGLTULBSNHNF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50582214
Affinity DataKd: 200nMAssay Description:Binding affinity to human N-terminal His6-tagged and thrombin cleavage fused BLVRB expressed in Escherichia coli BL21 (DE3) assessed as dissociation ...More data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:An enzyme activity assay for BLVRB was conducted. Since BLVRB catalyzes the NAD(P)H dependent readuction of FMN, changes in the NAD(P)H concentration...More data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding affinity to human N-terminal His6-tagged and thrombin cleavage fused BLVRB expressed in Escherichia coli BL21 (DE3) assessed as dissociation ...More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 1 hit for monomerid = 50582214
ITC DataΔG°: -9.12kcal/mole −TΔS°: 1.83kcal/mole ΔH°: -11.0kcal/mole logk: 4.93E+6
T: 25.00°C
T: 25.00°C