BDBM50055935 5-Ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione::5-ethyl-5-(1-methylbutyl)barbituric acid::5-ethyl-5-(pentan-2-yl)pyrimidine-2,4,6(1H,3H,5H)-trione::5-ethyl-5-(sec-pentyl)barbituric acid::CHEMBL448::Nembutal::PENTOBARBITAL::Pentobarbitone
SMILES CCCC(C)C1(CC)C(=O)NC(=O)NC1=O
InChI Key InChIKey=WEXRUCMBJFQVBZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50055935
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.28E+7nMAssay Description:Inhibitory concentration against IKr potassium channelMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Chantest
Curated by ChEMBL
Chantest
Curated by ChEMBL
Affinity DataIC50: 2.99E+5nMAssay Description:Inhibition of Cav1.2 current measured using PatchXpress automatic path clamp system in CHO cells expressing Cav1.2, beta-2 and alpha-2/delta-1 subuni...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Human)
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of [3H]R-(-)-14 from human FLAG-tagged alpha1 GABA A receptor expressed in HEK293S cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit beta-3(Human)
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 8.80E+4nMAssay Description:Displacement of [3H]R-(-)-14 from human FLAG-tagged beta3 GABA A receptor expressed in HEK293S cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Human)
University of Sassari
Curated by ChEMBL
University of Sassari
Curated by ChEMBL
Affinity DataEC50: 5.00E+4nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair