BDBM50299207 CHEMBL1558::CP-12299-1::Minipress::Minipress xl::PRAZOSIN HYDROCHLORIDE::Prazosin::[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-furan-2-yl-methanone; hydrochloride::[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-furan-2-yl-methanone; hydrochloride (Prazocin)::[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-furan-2-yl-methanone; hydrochloride (Prazosin)

SMILES COc1cc2c(cc1OC)nc(nc2N)N3CCN(CC3)C(=O)c4ccco4

InChI Key InChIKey=IENZQIKPVFGBNW-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299207   

TargetAlpha-1B adrenergic receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299207BDBM50299207(CHEMBL1558 | [4-(4-Amino-6,7-dimethoxy-quinazolin-...)
Affinity DataKi:  0.0270nMAssay Description:Binding affinity to recombinant human alpha-1B-Adr expressed in HEK cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299207BDBM50299207(CHEMBL1558 | [4-(4-Amino-6,7-dimethoxy-quinazolin-...)
Affinity DataKi:  0.130nMAssay Description:Binding affinity to recombinant human alpha-1A-Adr expressed in HEK cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed