BDBM50124417 1Alpha,25-Dihydroxy-22-Oxavitamin D3::22-Oxacalcitrol::Maxacalcitol::Prezios::SCH-209579

SMILES [H][C@@]1(CC[C@@]2([H])\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C)[C@H](C)OCCC(C)(C)O

InChI Key InChIKey=DTXXSJZBSTYZKE-ZDQKKZTESA-N

Data  5 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50124417   

TargetVitamin D3 receptor(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50124417(1Alpha,25-Dihydroxy-22-Oxavitamin D3 | 22-Oxacalci...)
Affinity DataEC50:  38nMAssay Description:Transactivation of VDR in human HaCaT cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50124417(1Alpha,25-Dihydroxy-22-Oxavitamin D3 | 22-Oxacalci...)
Affinity DataEC50:  41nMAssay Description:Transactivation of VDR in human Caco2 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50124417(1Alpha,25-Dihydroxy-22-Oxavitamin D3 | 22-Oxacalci...)
Affinity DataEC50:  160nMAssay Description:Activation of VDR in human HaCaT cells expressing lentiviral VDRE-luciferase vector assessed as VDRE-mediated transcriptional activity measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50124417(1Alpha,25-Dihydroxy-22-Oxavitamin D3 | 22-Oxacalci...)
Affinity DataEC50:  145nMAssay Description:Activation of VDR in human Caco2 cells expressing lentiviral VDRE-luciferase vector assessed as VDRE-mediated transcriptional activity measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50124417(1Alpha,25-Dihydroxy-22-Oxavitamin D3 | 22-Oxacalci...)
Affinity DataEC50:  0.855nMAssay Description:Activation of VDR in human Jurkat cells expressing lentiviral VDRE-luciferase vector assessed as VDRE-mediated transcriptional activity measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed