BDBM10799 (3R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-5-ol::6-hydroxy-N-propargyl-1(R)-aminoindan::Aminoindan deriv. (R)39u::CHEMBL371428::R-HPAI::rasagiline analogue
SMILES Oc1ccc2CC[C@@H](NCC#C)c2c1
InChI Key InChIKey=NRSDGDXUWMMUEV-GFCCVEGCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 10799
Affinity DataKi: 1.90E+3nM ΔG°: -7.80kcal/molepH: 7.5 T: 25°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically at 316 nm and 250 nm using kynuramine and benzylamine as substrates, respectively. ...More data for this Ligand-Target Pair
Affinity DataKi: 1.70E+4nM ΔG°: -6.50kcal/molepH: 7.5 T: 25°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically at 316 nm and 250 nm using kynuramine and benzylamine as substrates, respectively. ...More data for this Ligand-Target Pair
Affinity DataKi: 1.70E+4nMAssay Description:Inhibition constant against human recombinant Monoamine oxidase-B More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair