BDBM50312651 1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethyl-6-methyl-3-[2,2-difluoro-2-phenylethylamino]pyrazinone::CHEMBL1083499::RWJ-671818
SMILES [#6]-c1cnc(-[#7]-[#6]C(F)(F)c2ccccc2)c(=O)n1-[#6]-[#6](=O)-[#7]-[#6]-[#6]-[#8]\[#7]=[#6](\[#7])-[#7]
InChI Key InChIKey=IDCKXHIGLKQWMM-UHFFFAOYSA-N
Data 9 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50312651
Affinity DataKi: 1.30nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 2.40E+3nMAssay Description:Inhibition of tissue-type plasminogen activatorMore data for this Ligand-Target Pair
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 3.30E+3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of chymaseMore data for this Ligand-Target Pair
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of human leukocyte elastaseMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of urokinaseMore data for this Ligand-Target Pair
TargetCoagulation factor VII(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of cathepsin GMore data for this Ligand-Target Pair