BDBM50290086 (R)-N*1*-[2,2-Dimethyl-1-((R)-methylcarbamoyl)-propyl]-N*4*-hydroxy-2-isobutyl-succinamide::CHEMBL306412::Ro-37-9790

SMILES CNC(=O)[C@H](NC(=O)[C@H](CC(C)C)CC(=O)NO)C(C)(C)C

InChI Key InChIKey=QRXOZHSEEGNRFC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50290086   

LigandPNGBDBM50290086(Ro-37-9790 | (R)-N*1*-[2,2-Dimethyl-1-((R)-methylc...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human collagenase (MMP1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290086(Ro-37-9790 | (R)-N*1*-[2,2-Dimethyl-1-((R)-methylc...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human gelatinase B, MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290086(Ro-37-9790 | (R)-N*1*-[2,2-Dimethyl-1-((R)-methylc...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human stromelysin-1, MMP-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article