BDBM50376593 CHEMBL409225::SB-0304
SMILES C[C@@H](N1Cc2cc(O)ccc2C[C@H](N)C1=O)C(=O)N[C@H]1Cc2ccccc2CN(CC(N)=O)C1=O
InChI Key InChIKey=ACFTTXWQZSBVGL-OREJSRFESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50376593
Affinity DataKi: 160nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMAssay Description:Displacement of [3H]diprenorphine from human MOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]diprenorphine from human KOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.03E+4nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
Affinity DataEC50: 5.20nMAssay Description:Agonist activity at human MOR expressed in HEK293 cell membrane assessed as inhibition of forskolin-induced cAMP accumulation by by liquid scintillat...More data for this Ligand-Target Pair
Affinity DataEC50: 6.70nMAssay Description:Agonist activity at MOR/DOR in in NMRI mouse spinal cord assessed as reduction in spinal cord network activity by electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.08E+4nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Vrije Universiteit Brussel
Curated by ChEMBL
Vrije Universiteit Brussel
Curated by ChEMBL
Affinity DataIC50: 1.78E+4nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 3.64E+3nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Displacement of [3H]naloxone from MOR in rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Vrije Universiteit Brussel
Curated by ChEMBL
Vrije Universiteit Brussel
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Displacement of [3H]deltorphin2 from DOR in rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 567nMAssay Description:Agonist activity at MOR/DOR in in NMRI mouse frontal cortex assessed as reduction in spinal cord network activity by electrophysiology assayMore data for this Ligand-Target Pair