BDBM50306874 8-Hydroxy-6H-benzo[f][1,3]dioxolo[4',5':4,5]benzo[1,2,3-cd]indol-5-one::CHEMBL609040::SCH-535270

SMILES Oc1cccc2c1cc1NC(=O)c3cc4OCOc4c2c13

InChI Key InChIKey=OVACCXPNQSWBBB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50306874   

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306874(8-Hydroxy-6H-benzo[f][1,3]dioxolo[4',5':4,5]benzo[...)
Affinity DataIC50:  214nMAssay Description:Inhibition of CDC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306874(8-Hydroxy-6H-benzo[f][1,3]dioxolo[4',5':4,5]benzo[...)
Affinity DataIC50:  2.14E+3nMAssay Description:Inhibition of AUR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306874(8-Hydroxy-6H-benzo[f][1,3]dioxolo[4',5':4,5]benzo[...)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306874(8-Hydroxy-6H-benzo[f][1,3]dioxolo[4',5':4,5]benzo[...)
Affinity DataIC50:  35nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed