BDBM65399 US9533985, 178::US9533985, 53
SMILES Cn1c2cnccc2c(=O)n(-c2ccc(C[C@H](NC(=O)c3c(F)cc(NS(=O)(=O)c4ccc(cc4)-c4ccsc4)cc3F)C(O)=O)cc2)c1=O
InChI Key InChIKey=DGRUTRGOEXGZIA-NDEPHWFRSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 65399
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mouse)
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: <50nMpH: 9.6 T: 4°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mouse)
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 24nMpH: 9.6 T: 4°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
Affinity DataIC50: 740nMpH: 9.6 T: 4°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mouse)
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 2.80nMpH: 9.6 T: 4°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair