BDBM50477463 CHEBI:63334::Rolitetracycline::SO-15659::Syntetrin

SMILES CN(C)[C@@H]1C(O)=C(C(=O)NCN2CCCC2)C(=O)[C@@]2(O)C(O)=C3C(=O)c4c(O)cccc4[C@@](C)(O)[C@H]3C[C@@H]12

InChI Key InChIKey=HMEYVGGHISAPJR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50477463   

TargetIntegrase(Human immunodeficiency virus type 1)
Birla Institute of Technology and Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477463BDBM50477463(CHEBI:63334 | Rolitetracycline | SO-15659 | Syntet...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of HIV1 recombinant integrase 3'-processing activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Birla Institute of Technology and Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477463BDBM50477463(CHEBI:63334 | Rolitetracycline | SO-15659 | Syntet...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetInsulin-degrading enzyme(Human)
Univ. Lille

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477463BDBM50477463(CHEBI:63334 | Rolitetracycline | SO-15659 | Syntet...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant IDE expressed in Escherichia coli BL21 (DE3) cells using ATTO 655- Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed