BDBM103835 SPI-10::US11041859, Code SPI-10::US9791447, Compound SPI-10
SMILES Nc1ccc(\N=N\c2cccc(c2)S([O-])(=O)=O)c2ccccc12
InChI Key InChIKey=COAVSGQDMBDKLG-VHEBQXMUSA-M
Data 14 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 103835
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: >6.00E+7nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 3.42E+4nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 1.11E+4nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 3.64E+4nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 2.40E+3nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 2.50E+3nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease/Small ubiquitin-related modifier 1(Homo sapiens (Human))
City of Hope
US Patent
City of Hope
US Patent
Affinity DataIC50: >6.00E+4nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2/Small ubiquitin-related modifier 1(Homo sapiens (Human))
City of Hope
US Patent
City of Hope
US Patent
Affinity DataIC50: 3.42E+4nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+4nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease/Small ubiquitin-related modifier 2(Homo sapiens (Human))
City of Hope
US Patent
City of Hope
US Patent
Affinity DataIC50: 3.64E+4nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 2.40E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 2.50E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair