BDBM82417 CHEMBL461604::SR 48527

SMILES COc1cccc(OC)c1-c1cc(nn1-c1ccnc2cc(Cl)ccc12)C(=O)N[C@@H](C1CCCCC1)C(O)=O

InChI Key InChIKey=PXNTUYAGLGTUKX-MHZLTWQESA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 82417   

TargetNeurotensin(Guinea pig)
Hospital Saint-Antoine

Curated by PDSP Ki Database
LigandPNGBDBM82417(CHEMBL461604 | SR 48527)
Affinity DataKi:  1.70nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeurotensin(Guinea pig)
Hospital Saint-Antoine

Curated by PDSP Ki Database
LigandPNGBDBM82417(CHEMBL461604 | SR 48527)
Affinity DataKi:  4.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM82417(CHEMBL461604 | SR 48527)
Affinity DataKi:  644nMAssay Description:Displacement of [125I]NT at rat NTS2 overexpressed in CHOK1 cells after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM82417(CHEMBL461604 | SR 48527)
Affinity DataEC50:  217nMAssay Description:Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed