BDBM50030477 CHEBI:77317::CHEMBL458767::SR-12813
SMILES [#6]-[#6]-[#8]P(=O)([#8]-[#6]-[#6])[#6](=[#6]\c1cc(c(-[#8])c(c1)C([#6])([#6])[#6])C([#6])([#6])[#6])\P(=O)([#8]-[#6]-[#6])[#8]-[#6]-[#6]
InChI Key InChIKey=YQLJDECYQDRSBI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50030477
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Agonist activity at human pregnane X receptor expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 440nMAssay Description:Competitive binding affinity to human PXR LBD (111 to 434) by TR-FRET assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 220nMAssay Description:Activation of human PXRMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataEC50: 1.10E+3nMAssay Description:Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in ...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 60nMAssay Description:Agonist activity at human PXRMore data for this Ligand-Target Pair