BDBM25474 JMC516642 Compound 5::N-{2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl}-2,3-dihydro-1,4-benzodioxine-2-carboxamide::SR3677
SMILES CN(C)CCOc1cc(ccc1NC(=O)C1COc2ccccc2O1)-c1cn[nH]c1
InChI Key InChIKey=OQWZIAVXCYIZNN-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 25474
Affinity DataIC50: 3.20nMpH: 7.0 T: 22°CAssay Description:Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...More data for this Ligand-Target Pair
Affinity DataIC50: 3.97E+3nMpH: 7.3 T: 22°CAssay Description:Reaction mixture of kemptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 as substrate after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 7.49E+3nMpH: 7.3 T: 22°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+3nMpH: 7.3 T: 22°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair