BDBM50065271 3-(4-hydroxy-3,5-diisopropylbenzylidene)indolin-2-one::3-[1-(4-Hydroxy-3,5-diisopropyl-phenyl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one::CHEMBL85021::ST-280
SMILES CC(C)c1cc(\C=C2/C(=O)Nc3ccccc23)cc(C(C)C)c1O
InChI Key InChIKey=UGWOQEABVJFWIV-WQRHYEAKSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50065271
Affinity DataIC50: 1.75E+4nMAssay Description:Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK).More data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Insulin-like growth factor I receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of NOX4 expressed in HEK293 FS cells assessed as H2O2 production by H2O2/Tyr/LPO assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK)More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of EGFR in human A431 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.53E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Epidermal growth factor receptor (EGF RTK).More data for this Ligand-Target Pair