BDBM50653057 Elesclomol::GSK-842879::GSK-842879A::STA-4783::STA4783

SMILES CN(NC(=O)CC(=O)NN(C)C(=S)c1ccccc1)C(=S)c1ccccc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50653057   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50653057(Elesclomol | GSK-842879 | GSK-842879A | STA-4783 |...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of Hsp90 in Melphalan Resistant human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous on...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50653057(Elesclomol | GSK-842879 | GSK-842879A | STA-4783 |...)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of Hsp90 in human bortezomib-resistant ANBL6 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50653057(Elesclomol | GSK-842879 | GSK-842879A | STA-4783 |...)
Affinity DataIC50: 17nMAssay Description:Inhibition of Hsp90 in human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50653057(Elesclomol | GSK-842879 | GSK-842879A | STA-4783 |...)
Affinity DataIC50: 23nMAssay Description:Inhibition of Hsp90 in bortezomib Resistant human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50653057(Elesclomol | GSK-842879 | GSK-842879A | STA-4783 |...)
Affinity DataIC50: 49nMAssay Description:Inhibition of Hsp90 in human ANBL-6 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prolife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50653057(Elesclomol | GSK-842879 | GSK-842879A | STA-4783 |...)
Affinity DataIC50: 54nMAssay Description:Inhibition of Hsp90 in human U-266 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prolifer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed