BDBM50242276 CHEMBL486626::Sophoricoside

SMILES OC[C@H]1O[C@@H](Oc2ccc(cc2)-c2coc3cc(O)cc(O)c3c2=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI Key InChIKey=ISQRJFLLIDGZEP-CMWLGVBASA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50242276   

TargetInterleukin-5(Mouse)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50242276(CHEMBL486626 | Sophoricoside)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of mouse IL5-mediated mouse Y16 cell proliferation after 48 hrs by WST1 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterleukin-5(Mouse)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50242276(CHEMBL486626 | Sophoricoside)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition interleukin-5 in mouse Y16 cells after 48 hrs by WST-1 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterleukin-5(Mouse)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50242276(CHEMBL486626 | Sophoricoside)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of IL-5 in mouse pro-B Y16 cells after 48 hrs by WST1 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterleukin-5(Mouse)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50242276(CHEMBL486626 | Sophoricoside)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of IL5-mediated proliferation of mouse Y16 cells by WST1 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterleukin-5(Mouse)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50242276(CHEMBL486626 | Sophoricoside)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of IL-5 in mouse Y16 cells after 48 hrs by WST1 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterleukin-5 receptor subunit alpha(Mouse)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50242276(CHEMBL486626 | Sophoricoside)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterleukin-5(Mouse)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50242276(CHEMBL486626 | Sophoricoside)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of interleukin-5 in mouse Y16 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterleukin-5(Mouse)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50242276(CHEMBL486626 | Sophoricoside)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of mouse IL-5-induced cell proliferation in mouse Y16 cells after 48 hrs by WST-1 assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50242276(CHEMBL486626 | Sophoricoside)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Influenza A Jinan/15/90 H3N2 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50242276(CHEMBL486626 | Sophoricoside)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Influenza A PR/8/34 H1N1 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50242276(CHEMBL486626 | Sophoricoside)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Influenza A Jiangsu/10/2003 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterleukin-5(Mouse)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50242276(CHEMBL486626 | Sophoricoside)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of interleukin-5 in mouse Y16 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed