BDBM25083 6-(1H-indol-4-yl)-pteridin-2,4-diamine::6-(1H-indol-4-yl)pteridine-2,4-diamine::TG101110

SMILES Nc1nc(N)c2nc(cnc2n1)-c1cccc2[nH]ccc12

InChI Key InChIKey=WATUAWIVOKPMCL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 25083   

LigandPNGBDBM25083(6-(1H-indol-4-yl)pteridine-2,4-diamine | 6-(1H-ind...)
Affinity DataIC50: 64nMpH: 7.4 T: 2°CAssay Description:The luminescence-based kinase assay with recombinant phosphatidylinositol 3-kinase (Upstate Cell Signaling Solutions) was used for the determination ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2008
Entry Details Article
PubMed
LigandPNGBDBM25083(6-(1H-indol-4-yl)pteridine-2,4-diamine | 6-(1H-ind...)
Affinity DataIC50: 85nMpH: 7.4 T: 2°CAssay Description:The luminescence-based kinase assay with recombinant phosphatidylinositol 3-kinase (Upstate Cell Signaling Solutions) was used for the determination ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2008
Entry Details Article
PubMed
LigandPNGBDBM25083(6-(1H-indol-4-yl)pteridine-2,4-diamine | 6-(1H-ind...)
Affinity DataIC50: 107nMpH: 7.4 T: 2°CAssay Description:The luminescence-based kinase assay with recombinant phosphatidylinositol 3-kinase (Upstate Cell Signaling Solutions) was used for the determination ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2008
Entry Details Article
PubMed
LigandPNGBDBM25083(6-(1H-indol-4-yl)pteridine-2,4-diamine | 6-(1H-ind...)
Affinity DataIC50: 1.20E+3nMpH: 7.4 T: 2°CAssay Description:The luminescence-based kinase assay with recombinant phosphatidylinositol 3-kinase (Upstate Cell Signaling Solutions) was used for the determination ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2008
Entry Details Article
PubMed