BDBM50019966 2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::2-{4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL95636::Tefludazine

SMILES OCCN1CCN(CC1)[C@@H]1C[C@H](c2ccc(cc12)C(F)(F)F)c1ccc(F)cc1

InChI Key InChIKey=JSBWGXQXCRYYTG-PZJWPPBQSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50019966   

TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50019966(2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-6-trifluoromethy...)
Affinity DataIC50:  16nMAssay Description:Inhibition of [3H]spiperone binding to Dopamine receptor D2 from rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50019966(2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-6-trifluoromethy...)
Affinity DataIC50:  10nMAssay Description:Tested for the inhibition of [3H]-spiperone binding to dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50019966(2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-6-trifluoromethy...)
Affinity DataIC50:  14nMAssay Description:Binding affinity at dopamine D2 receptor by [3H]-Spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50019966(2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-6-trifluoromethy...)
Affinity DataIC50:  14nMAssay Description:Binding affinity towardst dopamine D2 receptor by displacement of [3H]-SPI radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50019966(2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-6-trifluoromethy...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of [3H]ketanserin binding to rat 5-hydroxytryptamine 2 receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50019966(2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-6-trifluoromethy...)
Affinity DataIC50:  14nMAssay Description:Binding affinity against Dopamine receptor D2 using [3H]spiroperidolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50019966(2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-6-trifluoromethy...)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of [3H]spiperone binding to 5-hydroxytryptamine 2 receptor from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50019966(2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-6-trifluoromethy...)
Affinity DataIC50:  17nMAssay Description:Inhibition of [3H]prazosin binding to alpha-1 adrenergic receptor from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(1A) dopamine receptor(Rat)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50019966(2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-6-trifluoromethy...)
Affinity DataIC50:  19nMAssay Description:Binding affinity towards dopamine receptor D1 by displacement of [3H]-SCH- radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed