BDBM50642713 Furaprevir::Tg-2349::TG-2349

SMILES CC(C)Oc1ccc(-c2nc(O[C@@H]3C[C@H]4C(=O)N[C@]5(C(=O)NS(=O)(=O)C6(C)CC6)C[C@H]5/C=C\CCCCC[C@H](NC(=O)OC5CCCC5)C(=O)N4C3)c3oc4ccccc4c3n2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50642713   

TargetNon-structural protein 4b(Hepacivirus hominis)TBA
LigandPNGBDBM50642713(Furaprevir | Tg-2349 | TG-2349)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Hepatitis C virus genotype 4a NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)TBA
LigandPNGBDBM50642713(Furaprevir | Tg-2349 | TG-2349)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Hepatitis C virus genotype 1a NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)TBA
LigandPNGBDBM50642713(Furaprevir | Tg-2349 | TG-2349)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Hepatitis C virus genotype 6a NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)TBA
LigandPNGBDBM50642713(Furaprevir | Tg-2349 | TG-2349)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)TBA
LigandPNGBDBM50642713(Furaprevir | Tg-2349 | TG-2349)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Hepatitis C virus genotype 5a NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)TBA
LigandPNGBDBM50642713(Furaprevir | Tg-2349 | TG-2349)
Affinity DataEC50:  1.60nMAssay Description:Inhibition of Hepatitis C virus genotype 3a NS4B expressed in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)TBA
LigandPNGBDBM50642713(Furaprevir | Tg-2349 | TG-2349)
Affinity DataIC50: 600nMAssay Description:Inhibition of Hepatitis C virus genotype 3a NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed