BDBM50653054 Tp-010::BTZO-1

SMILES O=c1nc(-c2ccccn2)sc2ccccc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50653054   

TargetMacrophage migration inhibitory factor(Human)
Takeda Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50653054(Tp-010 | BTZO-1)
Affinity DataIC50: 71nMAssay Description:Inhibition of [3H]-BTZO-1 binding to recombinant human C-terminal His-tagged MIF expressed in Escherichia coli BL21 (DE3) measured after 3 hrs by SPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
Takeda Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50653054(Tp-010 | BTZO-1)
Affinity DataKd:  88nMAssay Description:Binding affinity to BTZO-12 sensor chip immobilized human MIF expressed in Escherichia coli BL21 (DE3) by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
Takeda Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50653054(Tp-010 | BTZO-1)
Affinity DataKd:  157nMAssay Description:Binding affinity to recombinant human C-terminal His-tagged MIF expressed in Escherichia coli BL21 (DE3) at 400 nM incubated for 6 hrs using labelled...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Rattus norvegicus)
Takeda Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50653054(Tp-010 | BTZO-1)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant rat MIF expressed in Escherichia coli BL21 (DE3) assessed as reduction in tautomerase activity using L-dopachrome carboxy-m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed