BDBM50428367 CHEMBL2332119::Vegfrecine

SMILES NC(=O)C1=C(N)C(=O)C=C(Nc2ccccc2O)C1=O

InChI Key InChIKey=PAYLFJFRBIHGBV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50428367   

TargetVascular endothelial growth factor receptor 3(Human)
Institute of Microbial Chemistry (Bikaken)

Curated by ChEMBL
LigandPNGBDBM50428367(Vegfrecine | CHEMBL2332119)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Flt4 (unknown origin) after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Institute of Microbial Chemistry (Bikaken)

Curated by ChEMBL
LigandPNGBDBM50428367(Vegfrecine | CHEMBL2332119)
Affinity DataIC50: 11nMAssay Description:Inhibition of KDR (unknown origin) after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Institute of Microbial Chemistry (Bikaken)

Curated by ChEMBL
LigandPNGBDBM50428367(Vegfrecine | CHEMBL2332119)
Affinity DataIC50: 18nMAssay Description:Inhibition of GST-Flt1 kinase domain (unknown origin) expressed in baculovirus infected Sf9 cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Institute of Microbial Chemistry (Bikaken)

Curated by ChEMBL
LigandPNGBDBM50428367(Vegfrecine | CHEMBL2332119)
Affinity DataIC50: 480nMAssay Description:Inhibition of PDGFR-beta (unknown origin) after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Institute of Microbial Chemistry (Bikaken)

Curated by ChEMBL
LigandPNGBDBM50428367(Vegfrecine | CHEMBL2332119)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of EGFR (unknown origin) after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Institute of Microbial Chemistry (Bikaken)

Curated by ChEMBL
LigandPNGBDBM50428367(Vegfrecine | CHEMBL2332119)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of PDGFR-alpha (unknown origin) after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed