BDBM463987 US10787435, Example 001::WX001

SMILES CC(C)n1cnnc1-c1cccc(n1)N1CCc2ccc(cc2C1=O)-n1cnc(c1)C1CC1

InChI Key InChIKey=UCPTVOZWVQEEBK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 463987   

LigandPNGBDBM463987(WX001 | US10787435, Example 001)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM463987(WX001 | US10787435, Example 001)
Affinity DataIC50: 50nMAssay Description:Reagents:Base Reaction Buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOCompound T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2021
Entry Details
US Patent