BDBM50099586 2-(4-Hydroxy-phenyl)-3-methyl-1-(6-pyrrolidin-1-yl-hexyl)-1H-indol-5-ol::CHEMBL46903::ZK-119010

SMILES Cc1c(-c2ccc(O)cc2)n(CCCCCCN2CCCC2)c2ccc(O)cc12

InChI Key InChIKey=SACIXOLGIWUXTG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50099586   

TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099586(ZK-119010 | 2-(4-Hydroxy-phenyl)-3-methyl-1-(6-pyr...)
Affinity DataIC50: 25nMAssay Description:In vitro inhibition of [3H]17-beta-estradiol binding to human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099586(ZK-119010 | 2-(4-Hydroxy-phenyl)-3-methyl-1-(6-pyr...)
Affinity DataIC50: 69nMAssay Description:In vitro antagonist effect on estrogen receptor alpha transcriptional activation in MCF-7 cells against 10 pM 17-beta-estradiolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099586(ZK-119010 | 2-(4-Hydroxy-phenyl)-3-methyl-1-(6-pyr...)
Affinity DataIC50: 242nMAssay Description:In vitro inhibitory concentration against [3H]17-beta-estradiol binding to human estrogen receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed