BDBM50638470 Azenosertib::Zn-c3::ZN-C3::US20250304587, Compound ZnC3

SMILES C=CCn1c(=O)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2n1-c1ccc2c(n1)[C@@](O)(CC)CC2

InChI Key

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50638470   

TargetWee1-like protein kinase(Human)
Jiangsu Tasly Diyi Pharmaceutical Co.

US Patent
LigandPNGBDBM50638470(Azenosertib | Zn-c3 | ZN-C3 | US20250304587, Compo...)
Affinity DataIC50: 55nMAssay Description:WEE1 (Thermo Fisher, Cat #PR7373A) protein in buffer (50 mM HEPES pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% Brij-35) at 15 nM) in different concentration...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetWee1-like protein kinase(Human)
Jiangsu Tasly Diyi Pharmaceutical Co.

US Patent
LigandPNGBDBM50638470(Azenosertib | Zn-c3 | ZN-C3 | US20250304587, Compo...)
Affinity DataIC50: 567nMAssay Description:Inhibition of Wee1 in human U2OS cells assessed as reduction in CDK1 phosphorylation measured for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)