BDBM50638470 Azenosertib::Zn-c3::ZN-C3::US20250304587, Compound ZnC3

SMILES CC[C@]1(CCc2c1nc(cc2)N3c4c(cnc(n4)Nc5ccc(cc5)N6CCN(CC6)C)C(=O)N3CC=C)O

InChI Key InChIKey=OXTSYWDBUVRXFF-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50638470   

TargetWee1-like protein kinase(Human)
Galixir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50638470BDBM50638470(Azenosertib | Zn-c3 | ZN-C3 | US20250304587, Compo...)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetWee1-like protein kinase(Human)
Galixir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50638470BDBM50638470(Azenosertib | Zn-c3 | ZN-C3 | US20250304587, Compo...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetWee1-like protein kinase(Human)
Galixir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50638470BDBM50638470(Azenosertib | Zn-c3 | ZN-C3 | US20250304587, Compo...)
Affinity DataIC50: 567nMAssay Description:Inhibition of Wee1 in human U2OS cells assessed as reduction in CDK1 phosphorylation measured for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)