BDBM606918 US11685738, Compound A24::acid

SMILES OC(=O)CC(CCCCCCc1ccc2CCCNc2n1)c1cc(Cl)cc(c1)C(F)(F)F

InChI Key InChIKey=LCFNLMPNEUINNK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 606918   

TargetIntegrin alpha-V/beta-6(Human)
Ocuterra Therapeutics

US Patent
LigandPNGBDBM606918(US11685738, Compound A24 | acid )
Affinity DataIC50: 17.5nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent

TargetIntegrin alpha-V/beta-8(Human)
Ocuterra Therapeutics

US Patent
LigandPNGBDBM606918(US11685738, Compound A24 | acid )
Affinity DataIC50: 35.4nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent