BDBM606954 US11685738, Compound A21::acid

SMILES OC(=O)CC(CCCCCCc1ccc2CCCNc2n1)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=YSRHKDWMDJOMGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 606954   

TargetIntegrin alpha-V/beta-6(Human)
Ocuterra Therapeutics

US Patent
LigandPNGBDBM606954(US11685738, Compound A21 | acid )
Affinity DataIC50: 7.64nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent

TargetIntegrin alpha-V/beta-8(Human)
Ocuterra Therapeutics

US Patent
LigandPNGBDBM606954(US11685738, Compound A21 | acid )
Affinity DataIC50: 88.2nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent