BDBM50293573 4-(4-(2,4-dihydroxyphenyl)thiazol-2-ylamino)benzenesulfonamide::CHEMBL239103::cid_2175556

SMILES NS(=O)(=O)c1ccc(Nc2nc(cs2)-c2ccc(O)cc2O)cc1

InChI Key InChIKey=GOBNGGDCRDDODL-UHFFFAOYSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50293573   

TargetTransitional endoplasmic reticulum ATPase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50293573(4-(4-(2,4-dihydroxyphenyl)thiazol-2-ylamino)benzen...)
Affinity DataIC50: >5.00E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay

TargetTransitional endoplasmic reticulum ATPase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50293573(4-(4-(2,4-dihydroxyphenyl)thiazol-2-ylamino)benzen...)
Affinity DataIC50:  2.42E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay

LigandPNGBDBM50293573(4-(4-(2,4-dihydroxyphenyl)thiazol-2-ylamino)benzen...)
Affinity DataEC50:  2.30E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay

TargetFructose-1,6-bisphosphatase 1(Pig)
Boston College

Curated by ChEMBL
LigandPNGBDBM50293573(4-(4-(2,4-dihydroxyphenyl)thiazol-2-ylamino)benzen...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50293573(4-(4-(2,4-dihydroxyphenyl)thiazol-2-ylamino)benzen...)
Affinity DataEC50:  9.70E+3nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay

TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50293573(4-(4-(2,4-dihydroxyphenyl)thiazol-2-ylamino)benzen...)
Affinity DataEC50:  5.73E+3nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay

TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50293573(4-(4-(2,4-dihydroxyphenyl)thiazol-2-ylamino)benzen...)
Affinity DataIC50:  1.65E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50293573(4-(4-(2,4-dihydroxyphenyl)thiazol-2-ylamino)benzen...)
Affinity DataEC50:  1.71E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay