BDBM50063712 2-(2-Fluoro-phenylamino)-benzo[d][1,3]oxazin-4-one::CHEMBL10276::cid_2767221

SMILES Fc1ccccc1Nc1nc2ccccc2c(=O)o1

InChI Key InChIKey=GNYYAKGNULJHJU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50063712   

TargetNeuropilin-1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50063712(2-(2-Fluoro-phenylamino)-benzo[d][1,3]oxazin-4-one...)
Affinity DataIC50: >9.50E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063712(2-(2-Fluoro-phenylamino)-benzo[d][1,3]oxazin-4-one...)
Affinity DataIC50: >6.25E+4nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063712(2-(2-Fluoro-phenylamino)-benzo[d][1,3]oxazin-4-one...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed