BDBM50058420 (methylbenzoprim, MBP) 5-[4-(Benzyl-methyl-amino)-3-nitro-phenyl]-6-ethyl-pyrimidine-2,4-diamine::5-[4-(Benzyl-methyl-amino)-3-nitro-phenyl]-6-ethyl-pyrimidine-2,4-diamine::CHEMBL56170::cid_72438
SMILES CCc1nc(N)nc(N)c1-c1ccc(N(C)Cc2ccccc2)c(c1)[N+]([O-])=O
InChI Key InChIKey=NUFNKYNBZYIQDG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50058420
Affinity DataKi: 0.00900nMAssay Description:Inhibitory activity of compound against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:In vitro inhibitory concentration against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibitory activity against Dihydrofolate reductase from rat liver was evaluated using 90 microM dihydrofolic acid as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Pneumocystis carinii was evaluated using 90 microM dihydrofolic acid as substrateMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
University
Curated by ChEMBL
University
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Toxoplasma gondii was evaluated using 90 microM dihydrofolic acid as substrateMore data for this Ligand-Target Pair
TargetZinc finger protein GLI1(Mouse)
Burnham Center For Chemical Genomics
Curated by PubChem BioAssay
Burnham Center For Chemical Genomics
Curated by PubChem BioAssay
Affinity DataIC50: 1.57E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
University
Curated by ChEMBL
University
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibitory concentration against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair